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Cap A (acetic anhydride 12% in acetonitrile)
11659 -
for DNA synthesis
DOWNLOAD MSDS (PDF)Synonym: Acetic anhydride solution
CAS Number: 108-24-7
MDL number: MFCD00008705
Properties
| Related Categories | Carbonyl Compounds, Carboxylic Acid Anhydrides, Organic Building Blocks |
| grade | for DNA synthesis |
| total impurities | ≤0.005% water |
| density | 0.819 g/mL at 20 °C |
Description
Application
Reagent used in the phosphite triester method of oligonucleotide synthesis for the capping of the remaining free 5’-hydroxyl groups by acetylation. Reagent is suitable for use on Milligen 7500 synthesizers.
Preparation Note
filtered with a 0.1 μm filter
Price and Availability
Safety Information
| Symbol |    GHS02, GHS05, GHS06 |
| Signal word | Danger |
| Hazard statements | H225-H302-H315-H318-H331-H335 |
| Precautionary statements | P210-P261-P280-P305 + P351 + P338-P311 |
| Personal Protective Equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| Hazard Codes | F,Xn |
| Risk Statements | 11-20/21/22-37/38-41 |
| Safety Statements | 26-36/37/39 |
| RIDADR | UN 2924 3/PG 2 |
| WGK Germany | 2 |
| Flash Point(F) | 53.6 °F |
| Flash Point(C) | 12 °C |
Technical information & documentation associated with this product is available in the Safety & Documentation tab.
References
Merck 14,56
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